Renal Functional Reserve of Transplanted Kidneys

Renal Sinus Lipomatosis in Transplanted Kidneys: An Unusual Clinical Case

Renal sinus lipomatosis (RSL) represents an abnormal proliferation of the adipose tissue surrounding the renal pelvis of uncertain origin, associated with aging, obesity, steroid excess, infections, and calculosis. It represents a rare complication in transplanted kidneys, and, despite the accurate and prolonged radiological followup of transplanted organs, only a few cases of RSL have been des...

Histopathological findings in transplanted kidneys

Improvements in immunosuppression have reduced acute kidney allograft rejection and clinicians are now seeking ways to prolong allograft survival to 20 years and beyond. The primary cause of kidney allograft loss is still chronic rejection, followed by death with a functioning allograft and primary kidney disease recurrence. Thus, overcoming kidney allograft rejection remains the most important...

Lymphatic Neoangiogenesis in Transplanted Kidneys

Glomerular Filtration Rate and Renal Functional Reserve

Glomerular filtration rate (GFR) is usually accepted as the best overall index of kidney function in health and disease. Normal GFR varies according to age, sex, and body size. In young adults it is approximately 120-130ml/ min/1.73 m2 and declines with age1. A decrease in GFR precedes the onset of clinical kidney failure; therefore, a persistently reduced GFR is a specific indication of chroni...

Renal Functional Reserve and Renal Recovery after Acute Kidney Injury

Renal functional reserve (RFR) represents the capacity of the kidney to increase glomerular filtration rate (GFR) in response to certain physiological or pathological stimuli or conditions. Once baseline GFR is determined, RFR can be assessed clinically after an oral protein load or intravenous amino acid infusion. In clinical practice, baseline GFR displays variable levels due to diet or other...